NCR Online Journal

NK Cell Therapy Pipeline Analysis: 100+ Companies are Working to Improve the Treatment Space | DelveInsight

 Breaking News
  • No posts were found

NK Cell Therapy Pipeline Analysis: 100+ Companies are Working to Improve the Treatment Space | DelveInsight

November 10
14:49 2022
NK Cell Therapy Pipeline Analysis: 100+ Companies are Working to Improve the Treatment Space | DelveInsight

DelveInsight’s, “NK Cell Therapy Pipeline Insight, 2022,” report provides comprehensive insights about 100+ companies and 185+ pipeline drugs in NK Cell Therapy pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

 

Key takeaways from NK Cell Therapy Pipeline Insight Report

  • DelveInsight’s NK Cell Therapy Pipeline report depicts a robust space with 100+ active players working to develop 185+ pipeline therapies for NK Cell Therapy.
  • The leading NK Cell Therapy Companies such as ImmunityBio, Cantargia, CureTech, Dynavax, Cellid, Abivax, Affimed, Celularity, Glycostem Therapeutics (IPD Therapeutic), SYNIMMUNE, Celyad, Acepodia, Allife Medical Science and Technology, Bright Path Biotherapeutics, Cytovia Therapeutics, CytoImmune Therapeutics, Exacis Biotherapeutics,  Novocellbio, Kuur Therapeutics (Former name: Cell Medica), Fate Therapeutics, Feldan Therapeutics, iCell Gene Therapeutics, Innate Pharma, Nkarta Therapeutics, Surface Oncology, Kiadis Pharma, Vycellix, INmune Bio, CiMass, Glycostem, Five Prime Therapeutics, Multimmune GmbH, Ambicion, Bellicum Pharmaceuticals, CARsgen therapeutics, Kuur Therapeutics, Celyad, Dragonfly Therapeutics, GamidaCell, NantKwest, Asclepius Technology Company, AffimedTherapeutics, Apceth Biopharma, Zelluna Immunotherapy, Catamaran Bio, ONK Therapeutics, Orgenesis, Navrogen, NKMAX, Nektar Therapeutics, Affimed Therapeutics, HerbiCell, Bristol-Myers Squibb, CellProtect Nordic Pharmaceuticals, CytoVac, Green Cross Corporation, NantKwest, PersonGen BioTherapeutics (Suzhou), GT Biopharma (formerly Oxis International Inc.), Nektar Therapeutics, Artiva Biotherapeutics, Senti Biosciences, oNKo-innate, Affimed Therapeutics, and others.
  • Promising NK Cell Therapy Pipeline therapies such as NKTR-214, Monalizumab, Bemarituzumab, ALT 803, CellProtect, K-NK002, NK-92, WU-NK-101, Anti-CD33 CAR-NK cells, ALECSAT, and others
  • The companies and academics are working to assess challenges and seek opportunities that could influence Natural Killer (NK) cell therapy R&D. The therapies under development are focused on novel approaches to treat/improve Natural Killer (NK) cell therapy.
  • n the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Natural Killer (NK) cell therapy collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

 

Request a sample and discover the recent advances in NK Cell Therapy treatment @ NK Cell Therapy Pipeline Report

 

NK Cell Therapy Overview

Natural killer cells, also known as NK cells are a type of lymphocytes and are key components of the innate immune system. They are highly specific predators that play a major role in the host rejection of both tumors and viral infected cells. NK cells have cytotoxic small granules, which contain special proteins such as perforins and proteases, are known as granzymes in their cytoplasm. Perforins form pores in the cell membrane of the target cell through which the granzymes and associated molecules induce apoptosis. NK cells are derived from the common lymphoid progenitor cells (lymphoblasts), which also generate B and T lymphocytes. They differentiate and mature in the bone marrow, lymph nodes, spleen, tonsils, and thymus, where they then enter into the bloodstream.  NK cell therapy has been most successful in hematopoietic malignancies, such as leukemias. NK cell immunotherapy can be achieved by either activating endogenous NK cell response by administering NK stimulants or using exogenous NK cells via HSCT or adoptive cell transfer. Several strategies for NK cell immunotherapies for human cancer have been proposed to date. The upcoming technologies and recent advances in understanding the manipulation of NK cell activation and development have led to the hope that NK cells could be harnessed as immunotherapy for cancers and other diseases.

 

Recent Breakthroughs of NK Cell Therapy Treatment Landscape

  • In December 2017, Five Prime and Zai Lab announced a strategic collaboration for the development and commercialization of bemarituzumab in Greater China.
  • In February 2021, Nektar has entered into a clinical trial collaboration and supply agreement with Merck (known as MSD outside the United States and Canada) for a Phase II/III study of Bempegaldesleukin
  • In August 2019, Nektar Therapeutics and Bristol-Myers Squibb announced that the US FDA has granted Breakthrough Therapy Designation for investigational agent bempegaldesleukin (NKTR-214) in combination with Bristol-Myers Squibb’s Opdivo® (nivolumab) for the treatment of patients with previously untreated unresectable or metastatic melanoma.
  • NK-92 is being evaluated in Phase II stage of development for the treatment of stage IIIB & IV Merkel cell carcinoma as monotherapy and in combination with ALT-803, in Phase I stage of development for acute myeloid leukemia, Hematological Malignancies and solid tumors and in the Pre-IND phase for hepatocellular carcinoma and infectious disease.
  • K-NK002 is under Phase II clinical development by Kiadis Pharma for the treatment of acute myeloid leukemia and Myelodysplastic syndromes. CytoSen’s lead NK-cell therapy candidate, CSDT002-NK is now known as K-NK002 after the company being acquired by Kiadis Pharma in 2019.

 

Find out more about NK Cell Therapy Medication @ NK Cell Therapy Treatment

 

NK Cell Therapy Emerging Drugs

  • NKTR-214: Nektar therapeutics
  • Monalizumab: Innate Pharma
  • Bemarituzumab: Five Prime Therapeutics
  • ALT 803: ImmunityBio     
  • CellProtect: XNK Therapeutics
  • K-NK002: Kiadis Pharma
  • NK-92: ImmunityBio
  • WU-NK-101: Wugen
  • Anti-CD33 CAR-NK cells: PersonGen BioTherapeutics
  • ALECSAT: CytoVac     

 

DelveInsight’s NK Cell Therapy Pipeline report covers around 185+ products under different phases of clinical development like-

  • Late-stage products (Phase III and
  • Mid-stage products (Phase II and
  • Early-stage products (Phase I/II and Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration

 

Learn more about the novel and emerging NK Cell Therapy pipeline therapies @ NK Cell Therapy Clinical Trials

 

Scope of the NK Cell Therapy Pipeline Report

  • Coverage- Global
  • NK Cell Therapy Assessment by Product Type
  • NK Cell Therapy Assessment by Stage and Product Type
  • NK Cell Therapy Assessment by Route of Administration
  • NK Cell Therapy Assessment by Stage and Route of Administration
  • NK Cell Therapy Assessment by Molecule Type
  • NK Cell Therapy Assessment by Stage and Molecule Type
  • NK Cell Therapy Companies- ImmunityBio, Cantargia, CureTech, Dynavax, Cellid, Abivax, Affimed, Celularity, Glycostem Therapeutics (IPD Therapeutic), SYNIMMUNE, Celyad, Acepodia, Allife Medical Science and Technology, Bright Path Biotherapeutics, Cytovia Therapeutics, CytoImmune Therapeutics, Exacis Biotherapeutics,  Novocellbio, Kuur Therapeutics (Former name: Cell Medica), Fate Therapeutics, Feldan Therapeutics, iCell Gene Therapeutics, Innate Pharma, Nkarta Therapeutics, Surface Oncology, Kiadis Pharma, Vycellix, INmune Bio, CiMass, Glycostem, Five Prime Therapeutics, Multimmune GmbH, Ambicion, Bellicum Pharmaceuticals, CARsgen therapeutics, Kuur Therapeutics, Celyad, Dragonfly Therapeutics, GamidaCell, NantKwest, Asclepius Technology Company, AffimedTherapeutics, Apceth Biopharma, Zelluna Immunotherapy, Catamaran Bio, ONK Therapeutics, Orgenesis, Navrogen, NKMAX, Nektar Therapeutics, Affimed Therapeutics, HerbiCell, Bristol-Myers Squibb, CellProtect Nordic Pharmaceuticals, CytoVac, Green Cross Corporation, NantKwest, PersonGen BioTherapeutics (Suzhou), GT Biopharma (formerly Oxis International Inc.), Nektar Therapeutics, Artiva Biotherapeutics, Senti Biosciences, oNKo-innate, Affimed Therapeutics, and others
  • NK Cell Therapy Therapies- NKTR-214, Monalizumab, Bemarituzumab, ALT 803, CellProtect, K-NK002, NK-92, WU-NK-101, Anti-CD33 CAR-NK cells, ALECSAT, and others

 

Table of Content

  1. Introduction
  2. Executive Summary
  3. Natural Killer (NK) cell therapy: Overview
  4. Pipeline Therapeutics
  5. Therapeutic Assessment
  6. Late Stage Products (Phase III)
  7. NKTR-214: Nektar therapeutics
  8. Mid Stage Products (Phase II)
  9. CellProtect: XNK Therapeutics
  10. Early stage products (Phase I/II)
  11. Anti-CD33 CAR-NK cells: PersonGen BioTherapeutics
  12. Inactive Products
  13. Natural Killer (NK) cell therapy Key Companies
  14. Natural Killer (NK) cell therapy Key Products
  15. Natural Killer (NK) cell therapy- Unmet Needs
  16. Natural Killer (NK) cell therapy- Market Drivers and Barriers
  17. Natural Killer (NK) cell therapy- Future Perspectives and Conclusion
  18. Natural Killer (NK) cell therapy Analyst Views
  19. Natural Killer (NK) cell therapy Key Companies
  20. Appendix

 

Dive deep into rich insights for drugs for NK Cell Therapy treatment, visit @ New Drug for NK Cell Therapy Treatment

 

About Us

DelveInsight is a Business Consulting and Market research company, providing expert business solutions for the healthcare domain and offering quintessential advisory services in the areas of R&D, Strategy Formulation, Operations, Competitive Intelligence, Competitive Landscaping, and Mergers & Acquisitions.

Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Yash Bhardwaj
Email: Send Email
Phone: 9193216187
Address:304 S. Jones Blvd #2432
City: Las Vegas
State: NV
Country: United States
Website: https://www.delveinsight.com/

Related Articles